Brief Introduction of XNAPS

The Xmatrix Nucleic Acid Purification System (XNAPS) is a novel platform that provides a simple, safe, and efficient technology for nucleic acid extraction and purification from any organisms and sources. The surface-modified solid phase, Xmatrix, can bind specifically with free-form nucleic acid in an environmentally friendly aqueous condition. After the unbound impurities, such as proteins, lipids, are washed away from the mixture, the bound nucleic acid can be easily eluted and separated from the solid phase by nuclease-free water. The purified nucleic acid is ready for use in downstream applications (Fig.1).

XNAPS platform was specifically developed to overcome the disadvantages of current purification technologies which use toxic chaotropic salts, reagents that are known to inhibit enzymatic reactions and present storage, shipping, and handling challenges. Chaotropic-residue-free of the purificed nucleic acid exhibits improved activity in subsequent reactions. A series of XNAPS kits have been developed for applications requiring fast and easy preparation of highly pure DNA and RNA.

The latest generation of nucleic acid purification kits, based on this proprietary platform of XNAPS will enhance the performance of the purified DNA/RNA samples by improving dramatically both the quantity and quality of them.

Main advantages of XNAPS kits:
1. Fast process: Half of process time may saved.
2. Toxic-free: No phenol extraction, no ethanol precipitation, no TOXIC CHAOTROPIC SALTS are necessary in the system. ...............................No worry about waste disposal.
3. Ultra-purity: Xmatrix has high and specific binding capacity with nucleic acid. The OD 260 /OD 280 of purified .......................................... .................................nucleic acid reaches to .1.8-2.1.
4. High yield: 30 µg of high-copy plasmid can be purified from 3 ml culture, or, 10 µg of genomic DNA extracted from ................................ ...............................0.2 ml of .human .whole blood.
5. Low cost: Relatively lower pricres for high quality products.

.....................................................................Fig.1 Flow chart of XNAPS platform

Step1 Organism lysis

Step 2 Specific binding with nucleic acid

Step 3-1 Washing away of impurities

Step 3-2 Purified nucleic acid in binding form

Step 4 Elution and separation of nucleic acid